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Non-invasive caries management: vVARDIS in the context of global sustainable oral healthcare

  • 1.Fisher J, Özcan M, Krejci I, Banerjee A. Equity and integration; why the oral healthcare community urgently needs to reflect on its approach to caries management. Int J Equity Health. 2026 Jan 19;25(1):16. doi: 10.1186/s12939-025-02700-2.
  • 2.Alkilzy M, Santamaria RM, Schmoeckel J, Splieth CH. Treatment of carious lesions using self-assembling peptides. Adv Dent Res. 2018 Feb;29(1):42–7. doi: 10.1177/0022034517737025.
  • 3.Bröseler F, Tietmann C, Bommer C, Drechsel T, Heinzel-Gutenbrunner M, Jepsen S. Randomised clinical trial investigating self-assembling peptide P11-4 in the treatment of early caries. Clin Oral Investig. 2020 Jan;24(1):123–32. doi: 10.1007/s00784-019-02901-4.
  • 4.Welk A, Ratzmann A, Reich M, Krey KF, Schwahn C. Effect of self-assembling peptide P11-4 on orthodontic treatment-induced carious lesions. Sci Rep. 2020 Apr 22;10(1):6819. doi: 10.1038/s41598-020-63633-0.
  • 5.Godenzi D, Bommer C, Heinzel-Gutenbrunner M, Horst Keeper J, Peters K. Remineralizing potential of the biomimetic P11-4 self-assembling peptide on noncavitated caries lesions: a retrospective cohort study evaluating semistandardized before-and-after radiographs. J Am Dent Assoc. 2023 Oct;154(10):885–96.e9. doi: 10.1016/j.adaj.2023.07.009.
  • 6.Keeper JH, Kibbe LJ, Thakkar-Samtani M, Heaton LJ, Desrosiers C, Vela K, Amaechi BT, Jablonski-Momeni A, Young DA, MacLean J, Weyant RJ, Zandona AF, Sohn W, Pitts N, Frantsve-Hawley J. Systematic review and meta-analysis on the effect of self-assembling peptide P11-4 on arrest, cavitation, and progression of initial caries lesions. J Am Dent Assoc. 2023 Jul;154(7):580–91.e11. doi: 10.1016/j.adaj.2023.03.014.
  • 7.World Health Organization. WHO guideline on environmentally friendly and less invasive oral health care for preventing and managing dental caries. Geneva: World Health Organization; 2025 [cited 2026 Feb 9]. 74 p. Available from: https://minamataconvention.org/sites/default/files/documents/information_document/UNEP-MC-COP6-INF31-Add1-WHO-Dental-Amalgam_English.pdf.
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