Dental News - Ingenjörer utvecklar ny gel som främjar bentillväxt runt tandimplantat

Dental Tribune International

Sun. 20. April 2014

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UPPSALA, Sverige: Hur framgångsrik en behandling med tand- eller benimplantat blir beror i stor utsträckning på implantatens förmåga att binda samman med den intilliggande benvävnaden. En forskargrupp vid Uppsala universitet har utvecklat en ny beläggning som har visat sig ge en bättre sammanbindning mellan implantat och ben och samtidigt förhindrar att implantatet stöts bort.

Preliminära experiment vid Institut Laue-Langevin, ett internationellt forskningscenter i Grenoble, Frankrike, har visat att titanoxidytor som förses med en beläggning av bisfosfonat-modifierad hyalurongel binder proteinet BMP-2, som sedan frigörs på ett kontrollerat sätt när ytan kommer i kontakt med en lösning av kalciumjoner. Enligt forskarna kan denna process stimulera tillväxten av benvävnad runt implantatet.

Nästa steg är att testa liknande material för metallimplantat i syfte att försöka överföra resultaten till klinisk tillämpning.

”Vi föreställer oss att materialen i framtiden kommer att användas inom medicinen för att styra läkningsprocessen i ben”, säger prof. Dmitri Ossipov, författare till studien och docent vid Uppsala universitet.

Studien med titeln ”Polymeric smart coating strategy for titanium implants” publicerades i marsnumret av tidskriften Advanced Engineering Materials.

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