Research attacks perceived understanding of dental biofilm establishment and inhibition

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Research attacks perceived understanding of dental biofilm establishment and inhibition

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From left to right: Dr Kimberly R. Milleman, director at Salus Research; Dr Jeffery L. Milleman, director for clinical operations at Salus Research; Prof. Nicole Arweiler, director and chair of the department of periodontics and peri-implant diseases at the University of Marburg; and Mhari Coxon, president of the Oral Health Foundation. (Image: Dental Tribune International)
Johnson & Johnson

By Johnson & Johnson

Thu. 16. June 2022

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COPENHAGEN, Denmark: Clinical data released on 16 June at EuroPerio10 has revealed that Johnson & Johnson’s Listerine essential oil mouthrinse delivers 4.6 times greater interproximal plaque prevention above the gingival margin than does flossing.

In a dedicated symposium, three experts presented the findings of two revealing new studies which compared the use of Listerine essential oil mouthrinse and brushing with brushing and flossing alone for inhibiting the establishment of the dental biofilm.

The first study investigated the clinical efficacy of supervised mouth rinsing and flossing on plaque over the period of 12 weeks. It was led by research scientist Dr Jeffery L. Milleman, director for clinical operations and principal investigator at US-based clinical research team Salus Research, and provided evidence that rinsing with essential oil mouthrinse is superior to hygienist-conducted and hygienist-supervised flossing in preventing plaque build-up above the gingival margin. He said: “This study is further evidence that rinsing with an essential oil rinse is an effective adjunct to mechanical methods.”

Dr Kimberly R. Milleman, director, compliance specialist, organoleptic judge and gold standard examiner for Salus Research, presented the second study, which investigated the effects of essential oil mouthwash in oral hygiene regimens and showed that a regimen of brushing, flossing and rinsing with essential oil mouthrinse provided significant 28.4% greater reduction in interproximal plaque compared with brushing and flossing alone at 12 weeks. She said: “Mouthrinse covers the whole tooth, and when we grade plaque, we are grading it right along the gingival margin and interproximally.”

Both studies underline the fact that Listerine essential oil mouthrinse—in addition to mechanical cleaning—delivers more effective oral health.

Periodontist Prof. Nicole Arweiler, director and chair of the department of periodontics and peri-implant diseases at the University of Marburg’s dental school and hospital in Germany, commented: “Problems start when the dental biofilm becomes established on hard surfaces—the teeth, fillings, or other niches—and starts to develop a life of its own. We know that periodontal microflora influence our susceptibility to several diseases, including bacteraemia, endocarditis, diabetes, autoimmune disease and lung disease. We also find that patients with periodontitis have the same markers as for rheumatoid arthritis.”

She continued: “Mechanical hygiene measures to remove the dental biofilm are often insufficient. There are many people who do not brush or floss appropriately, plus there are situations when mechanical cleaning is not possible, such as when patients have sutures or following new implants. Additionally, there are groups, such as the elderly or people with disabilities, who find it difficult to adequately clean using brushing and flossing. An antibacterial mouthrinse can help to kill or ‘defang’ residual biofilms that dental patients have been unable to remove.”

Editorial note:

For details of the studies and references, please visit www.listerine.eu. A product sample can be requested at Booth C2.12.

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