Dental News - The role of melatonin in periodontal and periimplant bone homeostasis and regeneration

Dr. Pablo Galindo Moreno et al.

Mon. 17. October 2016

save

Background: Melatonin, a hormone produced primarily in the pineal gland, possesses a series of biological properties that appear to have an influence on bone homeostasis. Currently, little is known about how melatonin influences bone metabolism in periodontology and implantology.

Objective: The objectives of this study are (1) to review the properties of melatonin in regulating bone homeostasis; (2) to discuss its direct and indirect e ects on bone; and (3) to propose mechanisms for the use of melatonin as an agent to promote alveolar bone regeneration.

Conclusion: Melatonin positive regulation of bone formation and homeostasis, in combination with the inhibitory effects on bone resorption, highlights the potential use of melatonin as a marker of periodontal and periimplant bone-related diseases. In vitro and animal studies show promising results on the use of melatonin as a regenerative agent, although no clinical studies have yet been performed.

Editorial note: The full article was published in the 2/2016 issue of the Journal of Oral Science and Rehabilitation. Access the full article at www.dtscience.com.

To post a reply please login or register

New organisation to focus on bone and tissue regeneration

TURIN, Italy: The Bone, Biomaterials & Beyond (BBB) Academy is a newly formed international scientific and cultural association of professionals dedicated ...

“Being a role model is one of the most rewarding ways to transfer knowledge and skills”

Role models shape how dental students see the profession, their own potential and even their well-being. In a recent British Dental Journal special feature ...

The integral role of dental practices in recognising and responding to abuse and neglect

DUNDEE, UK: The complexities and under-reporting of abuse cases in society make it crucial for healthcare providers to remain vigilant and proactive in ...

Guided bone regeneration in smokers - Use of synthetic bone blocks

Bone grafts are used as a filler and scaffold to facilitate bone formation and promote wound healing if necessary. Bone grafting is possible because bone ...

Bones and machines: AI and the transformation of dental implantology

COLLEGE STATION, Texas, US: The methods dentists currently use to assess bone for implantation provide only indirect insights into bone mechanics. Since ...

AI-facilitated bone segmentation for the fabrication of bone-borne surgical guides

The use of 3D imaging has become the standard of care for diagnosis and treatment planning for many medical and dental procedures. Such imaging was first ...

Cytrans Granules: Exploring the role of an alloplast in regenerative therapy

VIENNA, Austria: At EuroPerio11, which is currently being held in Vienna in Austria, GC will present a dedicated symposium focusing on the clinical ...

Innovations in bone regeneration: An interview with Dr Matteo Chiapasco, Italy

On 30 September, notable expert and prolific author in oral and maxillofacial surgery Dr Matteo Chiapasco will be presenting at the annual scientific ...

Interview: Promoting preservation and regeneration of the natural biology with the IDR technique

Dr. José Carlos Martins da Rosa has a Master of Science in Prosthodontics and a PhD in implantology, and specializes in periodontics and prosthodontics. He...

The role of biology in the orthodontic practice

Orthodontic tooth movement results from forces applied to teeth, that evoke cellular responses in the teeth and their surrounding tissues, including the ...

Education

Live webinar
Tue. 12 May 2026
1:00 pm EST (New York)